Table 4 Validation of de facto drug targets
ID | Target proteins | Drug |
|---|---|---|
AD | PSEN1 (HSA:5663) | Begacestat (D08869) /Tarenflurbil (D09010) /Semagacestat (D09377) /Avagacestat (D09869) |
T2DM | INSR (HSA:3643) | Insulin (D00085) / etc. 19 insulin related drugs |
MEL | MAP2K (HSA:5604) | Cobimetinib (D10405) /Cobimetinib fumarate (D10615) |
PC | AR (HSA:367) | Testosterone (D00075) /Flutamide (D00586) /Bicalutamide (D00961) /Nilutamide (D00965) /Enzalutamide (D10218) |