Predicting clinically promising therapeutic hypotheses using tensor factorization

BMC Bioinformatics

Table 1 17 sources of target-indication evidence

Evidence Type	Sources
Animal models	Phenodigm
Genetics	European Variant Archive, Uniprot, Uniprot literature, GWAS catalog, STOPGAP [9]
Somatic mutation	Cancer Gene Census, European Variant Archive somatic
Literature	Europe PMC, TERMITE
mRNA disease expression	Expression Atlas, Internal expression data
mRNA tissue overexpression	GeneLogic, GTEx [49], Human Protein Atlas [50]
Pathways	Reactome, Metabase

Evidence data were obtained from Open Targets [1] except for TERMITE: www.scibite.com/products/termite; GeneLogic: GeneLogic Division, Ocimum Biosolutions, Inc., Internal expression data, and those explicitly referenced

ISSN: 1471-2105