Fig. 2

Behavior overview of variables listed in Table 1. a Heatmap representation of the correlation block matrix of the variables computed with AGO2_IN1 miRNA and mRNA expression profiles. The reported numbers are the correlation values, expressed in the range [− 100:100]. b ROC-AUC values obtained by classifying enriched/underrepresented genes associated with the variables computed with each IN expression profile. c Wilcoxon test p-values (log10) obtained by comparing the variable values associated with the enriched/underrepresented gene sets. In both b) and c), the variables computed with the three AGO2 IN profiles were used to distinguish enriched and underrepresented genes in AGO2-IP vs FT. The variables computed with the three GW182 IN profiles were used to distinguish enriched and underrepresented genes in GW182-IP vs FT.