Fig. 1
From: decompTumor2Sig: identification of mutational signatures active in individual tumors
The Alexandrov model of mutational signatures. The example signature shown here represents mutations caused by spontaneous deamination of 5-methylcytosine (COSMIC signature 1) and uses one flanking base in each direction of the mutated base. The location of mutations with respect to the transcription strand is not taken into consideration. The data were obtained from COSMIC at http://cancer.sanger.ac.uk/cosmic/signatures