Table 4 Description and symbol of synergy or antagonism in drug target combination of sensitive drug targets studies analyzed by CI method
From: Screening drug target combinations in disease-related molecular networks
Combination name | Value of Combination Index | Description | Graded Symbols |
|---|---|---|---|
PHGPx-TXAS | 0.8806 | Slight synergism | + |
TXAS-CYP4F3 | 0.91 | Nearly additive | + - |
PLA2-CYP4F3 | 0.92 | Nearly additive | + - |
PHGPx-CYP4F3 | 0.92 | Nearly additive | + - |
PLA2-PHGPx | 1.0442 | Nearly additive | + - |
TXAS-CYP4F3 | 1.1850 | Slight antagonism | - |
PLA2-TXAS | 1.45 | Antagonism | - - - |