Automated assessment of biological database assertions using the scientific literature

BMC Bioinformatics

Table 2 Examples of the top 5 words that occur in sentences where two proteins that interact also occur

	Term	Frequency	Example
1	Interact	33,128	As reported previously we also confirmed PHD2 interaction with FKBP38. [PMID: 21559462]
2	Activ	30,241	Another known protein that modulates PHD2 activity is FKBP38. [PMID: 20178464 ]
3	Express	29,863	BMP2 may promote PHD2 stabilization by down-modulating FKBP38 expression. [PMID: 19587783]
4	Bind	29,468	mIL-5 showed similar, high-affinity binding profiles to both gpIL-5r and hIL-5r. [PMID: 11132776]
5	Regulator	15,939	As a regulator of JNK, POSH is mainly implicated in the activation of apoptosis. [PMID: 17420289]

These words can be seen as approximating the semantics of the predicates linking the two proteins
Words in bold represent entities involved in an assertion, i.e., the entities and the predicate

ISSN: 1471-2105