Fig. 2

Visualization of the co-methylation network in Cytoscape. A total of 18,477 edges and 13,363 nodes make up this co-methylation network. The m6A sites are represented by blue nodes, and gray lines represent the high positive and negative correlation between each node. Majority of the sites (91.5%) were clustered into a huge module, and few sites share high correlation in methylation level within small modules. Four largest modules were amplificated and labelled in yellow, and the most significant Gene Ontology term of each module was labelled as well