Fig. 4
From: Genes with human-specific features are primarily involved with brain, immune and metabolic evolution
a The diagram represents the intersection between the set of genes with human-specific features and the set of genes that undergo differential expression upon activation of iPSC-derived neurons with KCl for 3 h. b The 12 human-specific differentially expressed genes and their mechanism of origin. c Gene expression was investigated by RT-qPCR using RNA from the same samples of active and inactive iPSC-derived neurons. Fold-change values were calculated relative to GAPDH expression. Statistical significance was performed using unpaired t-test (*p-value < 0.05; ***p value < 0.001)