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Fig. 2 | BMC Bioinformatics

Fig. 2

From: COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining

Fig. 2

COMBO-Pick flowchart. (1) A user-defined text specification file is imported; (2) Spatial feasibility control for 384-well format allowing at least 40 untreated wells is performed; (3) Alternative spatially feasible designs are suggested to the user; (4) Randomization of well destinations; (5) A plate destination specification for either exhaustive or pairwise drug combination experiments, compatible with Bridge, is produced per plate. 4-5 are repeated independently for all replicate plates, as specified by the user in (1)

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BMC Bioinformatics

ISSN: 1471-2105

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