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Fig. 4 | BMC Bioinformatics

Fig. 4

From: AutoCryoPicker: an unsupervised learning approach for fully automated single particle picking in Cryo-EM images

Fig. 4

Cryo-EM Contrast Transfer Correction (CTC) process. a The original cryo-EM image after the applying the averaging and normalization process through the EMAN2 software. b Histogram of the original cryo-EM image. c The cryo-EM image after applying the mid-range stretching based on the low-high intensity range. d Histogram of the image in (c). e The cryo-EM image after applying the contrast enhancement correction (CEC) and image adjustment. f The histogram of the cryo-EM image after applying the contrast enhancement correction (CEC)

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