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Table 3 Statistical evaluation AutoCryoPicker and EMAN2 performance using the Apoferritin and KLH images

From: AutoCryoPicker: an unsupervised learning approach for fully automated single particle picking in Cryo-EM images

Cryo-EM images Particle Shape Total Particles Number AutoCryoPicker EMAN2
TP FN FP TP FN FP
Apoferritin ImageĀ 1 Top-View 151 148 3 2 84 67 0
Apoferritin ImageĀ 2 Top-View 160 159 1 5 83 76 1
KLH image 1 Top-View 17 14 3 0 8 9 11
KLH image 2 Top-View 7 7 0 0 3 4 10
KLH image 1 Side-View 24 8 15 0 N/A N/A N/A
KLH image 2 Side-View 14 6 8 0 N/A N/A N/A
  1. The table reports TP: True Positive picking results where the correct particles are picked, FN: False Negative picking results where some good particles are missed, FP: False Positive picking results where the incorrect particles (other objects such as background or artificial objects) are picked as particles
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