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Table 4 Fanconi Anemia ORPHANET (ORPHA:84) database affected genes

From: Exploring the druggable space around the Fanconi anemia pathway using machine learning and mechanistic models

GENE NAME SYMBOL ENTREZ ID ENSEMBL ID OMIM
Fanconi Anemia complementation group F FANCF 2188 ENSG00000183161 603,467
Fanconi Anemia complementation group C FANCC 2176 ENSG00000158169 227,645
Breast cancer type 2 susceptibility protein BRCA2 675 ENSG00000139618 114,480
Breast cancer type 1 susceptibility protein BRCA1 672 ENSG00000012048 113,705
Fanconi Anemia complementation group E FANCE 2178 ENSG00000112039 600,901
RAD51 recombinase RAD51 5888 ENSG00000051180 114,480
Fanconi Anemia complementation group D2 FANCD2 2177 ENSG00000144554 227,646
Fanconi Anemia complementation group M FANCM 57,697 ENSG00000187790 609,644
DNA repair protein RAD51 homolog 3 RAD51C 5889 ENSG00000108384 602,774
Ubiquitin-conjugating enzyme E2 T UBE2T 29,089 ENSG00000077152 610,538
Fanconi Anemia complementation group B FANCB 2187 ENSG00000181544 300,514
Fanconi Anemia complementation group G FANCG 2189 ENSG00000221829 602,956
Fanconi Anemia complementation group I FANCI 55,215 ENSG00000140525 609,053
Fanconi Anemia complementation group L FANCL 55,120 ENSG00000115392 608,111
partner and localizer of BRCA2 PALB2 79,728 ENSG00000083093 114,480
SLX4 structure-specific endonuclease subunit SLX4 84,464 ENSG00000188827 613,278
Ring finger and WD repeat domain 3 RFWD3 55,159 ENSG00000168411 614,151
BRCA1 interacting protein C-terminal helicase 1 BRIP1 83,990 ENSG00000136492 114,480
ERCC excision repair 4, endonuclease catalytic subunit ERCC4 2072 ENSG00000175595 133,520
Mitotic arrest deficient 2 like 2 MAD2L2 10,459 ENSG00000116670 604,094
X-ray repair cross complementing 2 XRCC2 7516 ENSG00000196584 600,375
Fanconi Anemia complementation group A FANCA 2175 ENSG00000187741 227,650