Fig. 5
From: The MultiOmics Explainer: explaining omics results in the context of a pathway/genome database
Examples of two sets of routes generated by the MultiOmics Explainer that were considered to be both non-obvious and of likely biological relevance. a) Tryptophan inhibits the enzyme glutamine synthetase, which affects the production of arginine and therefore the expression of the ArgR regulon. b) Tryptophan inhibits enzyme anthranilate synthase (directly, by attenuation, and by TrpR repression), affecting the extent to which chorismate is directed towards production of tyrosine, which inhibits expression of AroP