Fig. 5

Network changes visualized in case of a representative functional sub-network. The representative figure shows the changes in weighted networks in case of proteins belonging to randomly selected GO:0044765 GO term. NW represents the weighted PPI network of interacting proteins in the 0 h time point, C04 and C12 correspond to PPI networks of interacting proteins in the 4 h and 12 h time point, respectively, in control, mock-transduced cells. H04 and H12 represent the weighted PPI network of interacting proteins in the 4 h and 12 h time point, respectively, in HIV vector-transduced cells. Red proteins are part of the functional sub-network, while black proteins are non-functional proteins. The weighted interactions are color-coded according to the protein-pair classification: functional – functional interactions are orange, non-functional – non-functional interactions are gray, and functional – non-functional interactions are green. The interaction strength is represented by the intensity of the color and thickness of the line: the higher the intensity of the color and the thickness of the line, the higher the interaction strength