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Fig. 5 | BMC Bioinformatics

Fig. 5

From: Prediction and interpretation of miRNA-disease associations based on miRNA target genes using canonical correlation analysis

Fig. 5

Schematic of our proposed model. First, we extracted miRNA-gene interactions and miRNA-disease associations from miRTarBase and HMDD, respectively. Then, target gene profiles and disease profiles for miRNAs were constructed. Third, canonical correlation analysis was performed to obtain correlated sets. Finally, novel miRNA-disease associations were predicted based on the weight vectors of the correlated sets.

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BMC Bioinformatics

ISSN: 1471-2105

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