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Table 2 Mouse elements yielded by a variant of the procedure that exploits only information derived from H and P

From: A purely bioinformatic pipeline for the prediction of mammalian odorant receptor gene enhancers

Sequence set of origin

mm10 coordinates

PSWMs with at least a significant hit (first round)

PSWMs with at least a significant hit (second round)

Notes

EPO/mouse MOE 1 Mb threshold

chr19:14694517–14,694,929

1, 4, 6, 8

1, 3, 4, 6, 8

Predicted enhancer in close proximity

EPO/mouse MOE 1 Mb threshold

chr14:49188564–49,189,030

1, 4, 6, 8

1, 2, 4, 5, 6, 8

On a retained intron

EPO/mouse MOE 1 Mb threshold

chr11:107760321–107,760,529

1, 8

1, 4, 6, 8

EPO/mouse MOE 1 Mb threshold

chr7:100639235–100,639,627

1

1, 5, 8

GERP/mouse MOE 1 Mb threshold

chr6:42869807–42,870,110

1, 2, 4, 5

1, 2, 4, 5, 6, 8

Overlaps with Sfaktiria

GERP/mouse MOE 1 Mb threshold

chr6:42869789–42,870,106

1, 2, 4, 5

1, 2, 4, 5, 6, 8

Overlaps with Sfaktiria

  1. Sets of evolutionarily conserved mouse sequences found within olfactory loci were screened for occurrences of position-specific weight matrices (PSWMs) obtained from multi-aligments of H and P-related sequences (no other known elements being included). Such sets were obtained intersecting the mouse MOE 1 Mb threshold list with mouse Ensembl tracks as either “36 eutherian mammals EPO low coverage” (EPO/mouse MOE 1 Mb threshold) or “GERP constrained elements” (GERP/mouse MOE 1 Mb threshold)