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Fig. 4 | BMC Bioinformatics

Fig. 4

From: NPA: an R package for computing network perturbation amplitudes using gene expression data and two-layer networks

Fig. 4

NPA of the oxidative stress network model scored with E-MTAB-2756 transcriptomic data. The bar graph on the left (panel a) represents the perturbation amplitude of the network model as a whole, and the network presentation on the right (panel b) shows an example of connected leading nodes common to all contrasts. The backbone NPA values with directionalities of inferred regulation are shown as bar graphs for each node. The green asterisk indicates that the node is a leading node in a given contrast. Highlighted nodes are the molecules discussed in the main text. The vocabulary for the BEL is provided in http://www.openbel.org/

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BMC Bioinformatics

ISSN: 1471-2105

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