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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Guide for library design and bias correction for large-scale transcriptome studies using highly multiplexed RNAseq methods

Fig. 4

Library biases and the correction in GEWAC study. a Hierarchical clustering of GEWAC subjects using the leukocyte expression profile without the library bias correction. Upper bar below tree represents the libraries, and lower bar represents the sample types. b PCA of the expression profile without the library bias correction. c Relation between the library quantity (x-axis of the left panel), proportions of mapped reads on protein coding genes (x-axis of the right panel), and the library redundancy (y-axis). d Hierarchical clustering of GEWAC subjects using the leukocyte expression profile with the library bias correction. The upper bar below tree represents the libraries, the lower bar represents the sample types

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