Fig. 3

Microplot examples. Solid and dotted lines represent different cohorts. The vertical axis represents microbe relative abundance, while the horizontal axis represents the immune readout. Three examples illustrate the different relationships that can be encapsulated in the sparkline-inspired microplot. a. A relationship between the microbe and the immune readout exists in one cohort but not the other which might suggest that the microbe is absent in the “flat line” group. b Differences in relationship between the microbe and immune readout across the two cohorts might suggest biological differences across the cohorts. c. The difference in dynamic range across the cohorts might suggest that the relationship captured by the longer line is driven by an outlier, with high values in both analytes