Fig. 9

Simplified miRNA-regulated HL-specific protein network consisting of 5 core miRNAs and 49 key HL-specific proteins. The core miRNAs are shown in blue rectangle and their name are also labeled in blue. The HL-specific proteins are shown in circle with different colors. The proteins in red color can be directly regulated by 5 core miRNAs. The direct miRNA regulation on protein is also shown in solid red line. The proteins in green color are indirectly regulated by the means of two interacting proteins. These proteins interaction is shown in solid black line. The proteins in gray color can’t be regulated by the core miRNAs in direct and indirect ways