| DE (%) | Up (%) | edgeR - robust | DESeq2 | limma - voom | ELMSeq | rSeqRobust |
|---|
| 1 | 50 | 0.8696 | 0.8944 | 0.8686 | 0.8924 | 0.9052 |
| | | (0.0378) | (0.0175) | (0.0389) | (0.017) | (0.0162) |
| 1 | 75 | 0.9085 | 0.9038 | 0.8961 | 0.9001 | 0.9057 |
| | | (0.0166) | (0.0146) | (0.0166) | (0.0163) | (0.0162) |
| 1 | 100 | 0.9108 | 0.898 | 0.9158 | 0.8992 | 0.8933 |
| | | (0.0228) | (0.0279) | (0.0205) | (0.0223) | (0.0237) |
| 10 | 50 | 0.9189 | 0.9176 | 0.9141 | 0.9092 | 0.9126 |
| | | (0.0089) | (0.009) | (0.0091) | (0.0091) | (0.008) |
| 10 | 75 | 0.9025 | 0.8999 | 0.8994 | 0.8892 | 0.8961 |
| | | (0.011) | (0.0099) | (0.0124) | (0.0122) | (0.0108) |
| 10 | 100 | 0.8558 | 0.8656 | 0.8646 | 0.854 | 0.8651 |
| | | (0.0263) | (0.0257) | (0.0217) | (0.029) | (0.0258) |
| 30 | 50 | 0.9156 | 0.9148 | 0.9082 | 0.9046 | 0.9037 |
| | | (0.0117) | (0.0108) | (0.0126) | (0.0097) | (0.0095) |
| 30 | 75 | 0.8963 | 0.9002 | 0.8879 | 0.8935 | 0.904 |
| | | (0.0134) | (0.008) | (0.0171) | (0.0126) | (0.0096) |
| 30 | 100 | 0.8655 | 0.8843 | 0.8489 | 0.8962 | 0.9215 |
| | | (0.02) | (0.0091) | (0.0244) | (0.0085) | (0.0073) |
| 50 | 50 | 0.8924 | 0.9006 | 0.8804 | 0.8888 | 0.8895 |
| | | (0.0146) | (0.012) | (0.0201) | (0.0129) | (0.0123) |
| 50 | 75 | 0.8837 | 0.9025 | 0.8761 | 0.8925 | 0.9241 |
| | | (0.0214) | (0.0095) | (0.0219) | (0.024) | (0.0083) |
| 50 | 100 | 0.6974 | 0.6906 | 0.6963 | 0.7648 | 0.854 |
| | | (0.0255) | (0.0261) | (0.0236) | (0.029) | (0.021) |
| 70 | 50 | 0.8985 | 0.9097 | 0.8948 | 0.8897 | 0.8806 |
| | | (0.0175) | (0.0101) | (0.0168) | (0.0144) | (0.0189) |
| 70 | 75 | 0.7951 | 0.7845 | 0.806 | 0.8163 | 0.8678 |
| | | (0.0203) | (0.0094) | (0.0236) | (0.0158) | (0.0253) |
| 70 | 100 | 0.5673 | 0.4875 | 0.5651 | 0.48 | 0.8623 |
| | | (0.0271) | (0.0255) | (0.0326) | (0.0261) | (0.024) |
| 90 | 50 | 0.8809 | 0.9014 | 0.8658 | 0.8841 | 0.8025 |
| | | (0.0184) | (0.0143) | (0.0233) | (0.0169) | (0.0367) |
| 90 | 75 | 0.6859 | 0.6557 | 0.6886 | 0.651 | 0.6562 |
| | | (0.0422) | (0.032) | (0.0399) | (0.0378) | (0.0565) |
| 90 | 100 | 0.2348 | 0.3932 | 0.2105 | 0.2978 | 0.4837 |
| | | (0.0256) | (0.0273) | (0.0355) | (0.0196) | (0.0576) |
- The table shows the percent of DE genes (DE %), percent of up-regulated genes among all the DE genes (Up %), and the mean AUCs (standard errors in parentheses) for all five methods with 10 simulated replicates. The highest AUC value is shown in bold
