Fig. 1

Identification, visualization and modeling of N-linked glycans onto the HIV-1 Env trimer. Protein surface representation of the high-mannose glycoform of the HIV-1 Env Trimer (PDB ID: 5fyl). Crystallographically-determined glycans are shown in Licorice representation. Each subunit (gp120 and gp41) is represented as a ribbon with sequons indicated with gray squares and the N-linked glycans shown above or below the sequon (upper left triangular panel). Glycosylator was used to produce a complex glycoform variant of the HIV-1 Env trimer by modeling glycans ab initio or extending existing glycans (lower right triangular panel)