Fig. 8From: Mathematical model of hypoxia and tumor signaling interplay reveals the importance of hypoxia and cell-to-cell variability in tumor growth inhibitionIndividual timecourse simulation of pAkt response under hypoxia. Simulation examples that result in an increase (a), decrease (b), or no change (c) in pAKT response upon reduction in O2 levels as identified by horizontal bar over plotBack to article page