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Table 2 MiniScrub improves read error correction in the metagenome setting

From: De novo Nanopore read quality improvement using deep learning

 

No scrubbing

With scrubbing

Avg. coverage pct.

47.04%

52.71%

Avg. mean coverage depth

3.08

3.34

Pct. of genomes above 1.0 coverage depth

46.67%

60.00%

  1. Reads from the high complexity (HC) dataset [31], both with and without scrubbing beforehand, were corrected using Canu’s [19] error correction module and then aligned to their reference genomes with GraphMap [26]. The statistics in the table are averages across all source genomes that had non-zero coverage. Applying scrubbing before read error correction improves average coverage percentage and the average mean coverage depth across the source genomes, and leads to a larger number of source genomes having a mean coverage depth of at least 1.0 Best performance numbers are shown in bold
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BMC Bioinformatics

ISSN: 1471-2105

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