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Table 1 Assess of FDR control and TPr when controlling estimated FDR at 0.05

From: Modeling allele-specific expression at the gene and SNP levels simultaneously by a Bayesian logistic mixed regression model

Method True FDR TPr(%)
  gene SNP gene-SNP gene SNP gene-SNP
BLMRM 0.053 0.028 0.059 66.37 60.82 17.51
  (0.006) (0.004) (0.014) (0.87) (1.80) (1.65)
BLMRM 0.060 0.030 0.094 68.87 56.82 17.50
(pure Laplace) (0.006) (0.002) (0.008) (0.29) (1.19) (0.91)
GLMM 0.073 0.006 0.625 68.66 57.20 86.72
  (0.010) (0.002) (0.004) (1.52) (1.49) (0.86)
MBASED 0.358 0.032 - 91.34 64.32 -
  (0.006) (0.005) - (0.54) (1.51) -
ANOVA 0.194 - - 82.02 - -
  (0.007) - - (1.04) - -
Binomial 0.314 - - 88.26 - -
  (0.003) - - (0.80) - -