Metabolic disassembler for understanding and predicting the biosynthetic units of natural products

BMC Bioinformatics

Table 6 Accuracy of the baseline workflow for each metabolic map

Map number	Name of the pathway map	Correct	Incorrect	Number of molecules	Accuracy
00231	Puromycin biosynthesis	4	6	10	0.400
00232	Caffeine metabolism	11	3	14	0.786
00254	Aflatoxin biosynthesis	13	8	21	0.619
00261	Monobactam biosynthesis	9	15	24	0.375
00311	Penicillin and cephalosporin biosynthesis	8	4	12	0.667
00331	Clavulanic acid biosynthesis	8	0	8	1.000
00332	Carbapenem biosynthesis	13	10	23	0.565
00333	Prodigiosin biosynthesis	1	10	11	0.091
00401	Novobiocin biosynthesis	13	5	18	0.722
00402	Benzoxazinoid biosynthesis	6	0	6	1.000
00403	Indole diterpene alkaloid biosynthesis	13	17	30	0.433
00404	Staurosporine biosynthesis	11	21	32	0.344
00405	Phenazine biosynthesis	4	21	25	0.160
00521	Streptomycin biosynthesis	4	11	15	0.267
00524	Neomycin, kanamycin and gentamicin biosynthesis	39	30	69	0.565
00525	Acarbose and validamycin biosynthesis	20	9	29	0.690
00901	Indole alkaloid biosynthesis	30	26	56	0.536
00940	Phenylpropanoid biosynthesis	25	30	55	0.455
00941	Flavonoid biosynthesis	42	21	63	0.667
00942	Anthocyanin biosynthesis	32	31	63	0.508
00943	Isoflavonoid biosynthesis	32	27	59	0.542
00944	Flavone and flavonol biosynthesis	37	12	49	0.755
00945	Stilbenoid, diarylheptanoid and gingerol biosynthesis	10	13	23	0.435
00950	Isoquinoline alkaloid biosynthesis	31	68	99	0.313
00960	Tropane, piperidine and pyridine alkaloid biosynthesis	16	42	58	0.276
00965	Betalain biosynthesis	7	13	20	0.350
00966	Glucosinolate biosynthesis	47	6	53	0.887
01058	Acridone alkaloid biosynthesis	12	3	15	0.800
	Total (without redundancy)	490	453	943	0.520

ISSN: 1471-2105