Fig. 4

30.8% of the original TF binding data are found to be the TF module-inferred functional binding pairs. In the original Harbison ChIP dataset, 4.5% of the binding targets overlap with the TF knock-out experiments of Hu et al. These are called the knockout-inferred direct regulatory targets or knockout-inferred functional binding targets in this research. And utilizing the mined-out TF regulatory modules, extra 26.3% of the target genes were derived as pure module-inferred functional binding targets. In total, 30.8% of target genes are the module-inferred functional pairs