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Table 4 Performance comparison between iProDNA-CapsNet and other state-of-the-art methods

From: iProDNA-CapsNet: identifying protein-DNA binding residues using capsule neural networks

Method

Setting

ACC (%)

SN (%)

SP (%)

PR (%)

MCC

BindN

Unknown

79.15

45.64

80.90

11.12

0.143

ProteDNA

Unknown

95.11

4.77

99.84

60.30

0.160

MetaDBSite

Unknown

90.41

34.20

93.35

21.22

0.221

DP-Bind

Unknown

81.40

61.72

82.43

15.53

0.241

DNABind

Unknown

79.78

70.16

80.28

15.70

0.264

BindN+

FPR ≈ 5%

91.58

24.11

95.11 a

20.51

0.178

 

FPR ≈ 15%

83.69

50.81

85.41

15.42

0.213

TargetDNA

FPR ≈ 5%

90.89

45.50 a

93.27

26.13

0.300

 

FPR ≈ 15%

84.52 b

60.22

85.79 b

18.16

0.269

iProDNA-CapsNet

FPR ≈ 5%

92.38 a

42.17

94.93

29.78 a

0.315 a

 

FPR ≈ 15%

84.05

65.38 b

85.00

18.17 b

0.285 b

  1. Values which are significantly higher than the others are in bold with aFPR ≈ 5% and bFPR ≈ 15%