Fig. 5

METROID comparison to other methods on simulated imaging data (SNR similar to experimental data). a Representative traces in a ROI of AP filtered signal by different methods. Black circles represent true AP signal, dark gray dotted lines are ROI mean over time, gray continuous lines are BkS, light gray dashed lines are BkSD, pink dot-dashed lines are the average of 10 videos (avg10), purple dot-dashed lines are the average of 400 videos (avg400), olive green thick dashed lines are METROID output with default parameters, blue continuous lines are METROID optimized with ICA (onset and end times supplied), and green continuous lines are METROID with wICA (onset and end times supplied). b E_{r_Amp} means of each method (N = 32). Vertical lines represent standard error of the means. cr means. d Representative traces in a ROI closer to the cathode side of electroporation filtered signal by different methods. Same color scheme as in (a), except that red continuous lines are METROID optimized with PCA (onset and end times supplied, m = 3), and orange continuous lines are METROID optimized with wPCA (onset and end times supplied, m = 3). e Peak E_{r_Amp} means. f Stationary E_{r_Amp} means