Fig. 5
From: Drug-target interactions prediction using marginalized denoising model on heterogeneous networks
Illustration of latent global association. The solid line shows the existing association, and the dashed line shows latent global association. As shown in (a), if drug di is highly similar to drug dl, dl has an interaction with target tk, and tk is highly similar to target tj, then di has an interaction with tj with high probability. As shown in (b), if both drugs di and dk have an interaction with target tl, and dk has an interaction with target tj, then di has an interaction with tj with high probability