Fig. 4From: SimuSCoP: reliably simulate Illumina sequencing data based on position and context dependent profilesThe statistics of JSD values of each base substitution. Given a base substitution type, the frequency of the substitution in each base position is measured, and Jensen-Shannon Divergence is used to evaluate the similarity between the real and inferred probability distributions. The statistics of JSD values for a given substitution are obtained by analyzing all 3-mer forms of the substitution. For instance, substitution types such as (AAA > AAC), (ACA > ACC) and (TTA > TTC) are the 3-mer forms of base substitution A > CBack to article page