Computationally identifying hot spots in protein-DNA binding interfaces using an ensemble approach

BMC Bioinformatics

Table 3 The rankings of the 19 selected features

Rank	Feature name	Type	Rank	Feature name	Type
1	PSSM(R)	Sequence	11	Lse score	Sequence
2	H-Bond in HBPLUS	Structure	12	phi in SPOT-1D	Sequence
3	ALPHA in Xssp	Structure	13	COMBINED2 score in ENDES	Structure
4	Current_flow_closeness_centrality	Network	14	ACC in Xssp	Structure
5	Q3_prob_3 in NetSurfp2	Sequence	15	RSA in NetSurfp2	Sequence
6	HSEa-u in SPOT-1D	Exposure	16	P(8-G) in SPOT-1D	Sequence
7	COMBINED1 score in ENDES	Structure	17	CN in hsexpo	Exposure
8	SIDESCORE score in ENDES	Structure	18	Conservation score	Sequence
9	Q8_prob_1 in NetSurfp2	Sequence	19	Blosum(E)	Sequence
10	P(8-I) in SPOT-1D	Sequence

These features fall intro four types, i.e., network features, exposure features, structure features and sequence features

ISSN: 1471-2105