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Table 1 Associations with the highest prediction scores

From: NEDD: a network embedding based method for predicting drug-disease associations

Rank Drug Disease References
ID (DrugBank) Name ID (OMIM) Name
1 DB01202 Levetiracetam 208,700 ATAXIA WITH MYOCLONIC EPILEPSY AND PRESENILE DEMENTIA [35]
2 DB01181 Ifosfamide 267,730 RETICULUM CELL SARCOMA
3 DB00937 Diethylpropion 303,110 CHOROIDEREMIA, DEAFNESS, AND MENTAL RETARDATION
4 DB00584 Enalapril 161,900 RENAL FAILURE, PROGRESSIVE, WITH HYPERTENSION; RFH1 [36]
5 DB00444 Teniposide 276,300 MISMATCH REPAIR CANCER SYNDROME; MMRCS
6 DB01070 Dihydrotachysterol 277,440 VITAMIN D-DEPENDENT RICKETS, TYPE 2A; VDDR2A [37]
7 DB00176 Fluvoxamine 131,300 CAMURATI-ENGELMANN DISEASE; CAEND
8 DB00710 Ibandronate 167,320 INCLUSION BODY MYOPATHY WITH EARLY-ONSET PAGET DISEASE WITH OR WITHOUT FRONTOTEMPORAL DEMENTIA 1; IBMPFD1 [38]
9 DB00710 Ibandronate 602,080 PAGET DISEASE OF BONE 2, EARLY-ONSET; PDB2 [38]
10 DB00282 Pamidronic acid 602,080 PAGET DISEASE OF BONE 2, EARLY-ONSET; PDB2 [39]
11 DB01551 Dihydrocodeine 147,530 INSENSITIVITY TO PAIN WITH HYPERPLASTIC MYELINOPATHY
12 DB00500 Tolmetin 147,530 INSENSITIVITY TO PAIN WITH HYPERPLASTIC MYELINOPATHY
13 DB00136 Calcitriol 241,519 HYPOPHOSPHATEMIA, RENAL, WITH INTRACEREBRAL CALCIFICATIONS [40]
14 DB00214 Torasemide 256,370 NEPHROTIC SYNDROME, TYPE 4; NPHS4 [41]
15 DB01120 Gliclazide 600,496 MATURITY-ONSET DIABETES OF THE YOUNG, TYPE 3; MODY3 [42]