Fig. 1
From: MutEnricher: a flexible toolset for somatic mutation enrichment analysis of tumor whole genomes
Schematic representation of MutEnricher’s analysis procedures. MutEnricher’s coding module determines enrichment of genic non-silent somatic mutations (red stems) against a background that includes silent (black stems) and non-coding (purple stems) mutations, whereas its noncoding module determines enrichment of non-coding mutations in user-defined genomic intervals, which may include promoters (red region), enhancers (blue regions), etc. The lower boxes summarize MutEnricher’s procedures, describing inputs, analytical steps, and outputs