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Table 1 Comparison of centrality scores of essential proteins versus non-essential proteins

From: Comprehensive host-pathogen protein-protein interaction network analysis

Centrality Essential Proteins Non-Essential Proteins t-score p-value
Mean Standard Error Mean Standard Error
Degree 38.41 0.84 20.12 0.33 20.14 2.7e-88
Radiality 0.76 0.0004 0.73 0.0003 38.68 9.4e-311
Closeness 0.32 0.0004 0.3 0.0002 40.7 1.2e-313
Betweenness 0.0002 0.00002 0.00007 0.000003 6.45 1.2e-10
Clustering Coefficient 0.095 0.0017 0.082 0.0014 5.78 7.9e-09
Average Shortest Path 3.15 0.004 3.36 0.003 −38.68 9.4e-311
Topological Coefficient 0.096 0.0015 0.138 0.0013 −20.55 1.1e-92
Neighborhood Connectivity 233.93 4.84 206.64 3.28 4.66 3.1e-06
Eigen vector centrality 0.03 0.0006 0.01 0.0002 29.02 1.8e-176
Page rank centrality 0.0007 0.00002 0.0004 0.000005 15.06 1.3e-50