Table 4 Anti-depression Western drugs

Nefazodone

0.33333

0.0794702

4.1944025

Cases of life-threatening hepatic failure have been reported in patients treated with nefazodone.

2–4 h

Milnacipran

0.62295879

0.1589404

3.9194490

Oral LD₅₀ rat: 213 mg/kg

6–8 h

Mianserin

0.34600026

0.1192

2.9026867

Oral LD₅₀ rat: 780 mg/kg

10–17 h

Trazodone

0.81612163

0.31788079

2.5673826

Oral LD₅₀ rat: 690 mg/kg

7.3 +/−  0.8 h.

Nortriptyline

0.3283245

0.1589404

2.0657082

Oral LD₅₀ rat: 405 mg/kg

26 h

Duloxetine

0.99170246

0.91390728

1.0851237

Fatalities have been reported with doses of 1000 mg involving both mixed drugs as well as duloxetine alone

12 h

Clomipramine

0.41045464

0.39735099

1.03297751

One death involved a patient suspected of ingesting a dose of 7000 mg. The second death involved a patient suspected of ingesting a dose of 5750 mg.

32 h

Reboxetine

0.36668174

0.47682119

0.76901309

Reports of seizures (rare) have been reported

12.5 h

Mirtazapine

0.59422385

0.95364238

0.62310972

Oral LD₅₀ rat: 830 mg/kg in male Swiss mice

20–40 h

Venlafaxine

0.81547802

1.43046358

0.57007954

Overdose of venlafaxine is typically associated with mild symptoms

5 h

Citalopram

0.92540653

1.82781457

0.50629125

Oral LD₅₀ rat:179 mg/kg

35 h

Fluoxetine

0.86558296

5.16556291

0.16756798

In a report that included 234 fluoxetine overdose cases, it was concluded that symptoms resulting from fluoxetine overdose were generally minor and short in duration

1–3 days