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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Differential gene regulatory pattern in the human brain from schizophrenia using transcriptomic-causal network

Fig. 2

a Identified transcriptomic-causal network and a close-up. Each node represents a gene. Genes associated with SCZ are depicted in blue. b Distribution of the connectivity of the genes with genetic variants (left) and the genes without genetic variants (right) in the network. c Stability of the network after permutation of broadcaster genes (blue curve) and receptors genes (red curve). d Presentation of in-degree and out-degrees of genes associated with SCZ in the network. Single color bars in yellow or purple are corresponding to broadcaster and receptor genes respectively while bars with both colors are representing mediator genes. e Venn diagram groups SCZ-associated genes based on the type of studies that previously found their association (psych.cnv: Psychiatric study of copy number variation; SCZ.denovo.nonsyn: SCZ study of non-synonymous de novo mutations; SCZ.gwas: SCZ study of genome wide association studies; SCZ.denova.lof: SCZ study of Loss-of-function de novo mutations)

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BMC Bioinformatics

ISSN: 1471-2105

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