Fig. 6From: NIMBus: a negative binomial regression based Integrative Method for mutation Burden AnalysisSchematic plot of network analysis: The associated values of \({\mu }_{m},{\gamma }_{m}\) are extracted from NIMBus for each of the \(m\) genes, potentially located on different chromosomes. A single P-value, \({p}_{m}\), is obtained for each gene. Fisher’s method is used to combine all of the P-values into a final P-value for the network, \({p}_{network}\)Back to article page