Table 1 The mapping of each RNA feature into a layer of the auditory display

As the sequence is processed each is sonified to create a constant audio stream

Nucleotide

4

Throughout the genome

Di-nucleotide

16

Throughout the genome

GC Content (10 bp)

10

Throughout the genome

GC Content (100 bp)

10

Throughout the genome

Three of the same nucleotide repeats

Example: the poly-A tail

4

Anytime when condition is true

Codons (translation only)

Codon Frame 1

20

Between start and stop codons

Codon Frame 2

20

Between start and stop codons

Codon Frame 3

20

Between start and stop codons

Trinucleotides (transcription only)

Only the 1st and 3rd nucleotides are considered

16

Throughout the genome

Untranslated regions

Intragenic UTR regions (excluding 5′ and 3′ UTRs)

16

At genomic regions defined by GenBank metadata [2]

Individual nucleotides were mapped to higher octaves ranges for the sake of audio clarity

Transcription regulating sequences (TRS)

Each nucleotide in TRS1 through to TRS10

16

Polyprotein cleavage sites (translation only)

Nucleotides that code for the cleaved AA residues

4

Stem and Loop regions (SL)

Each nucleotide in the identified region

16