Skip to main content

Table 6 Comparison with existing methods on the independent test sets

From: m5CPred-SVM: a novel method for predicting m5C sites of RNA

Species Model Sn (%) Sp (%) Pre (%) Acc (%) Mcc F1-score AUROCa
H. sapiens RNAm5Cfinder 37.7 88.4 76.5 63.1 0.303 0.505 0.635
iRNA-m5C 42.1 46.4 43.9 44.2 -0.116 0.429
iRNAm5C-PseDNC 4.35 97.1 60.1 50.7 0.039 0.081
RNAm5CPred 71.0 66.7 68.1 68.9 0.377 0.695 0.772
our method 75.4 79.7 78.8 77.5 0.551 0.77 0.858
M. musculus RNAm5Cfinder 38.6 78.9 64.5 58.8 0.191 0.483 0.593
iRNA-m5C 0.61 99.8 75.1 50.2 0.032 0.012
our method 67.9 74.9 73.0 71.4 0.429 0.704 0.775
A. thaliana iRNA-m5C 72.4 75.6 73.5 74.1 0.481 0.729
PEA-m5C 43.2 45.4 43.8 44.3 -0.114 0.454
our method 75.5 76.1 76.0 75.8 0.516 0.757 0.836
  1. Bold numbers indicate the highest values in each column for different species
  2. aThere are no predicted scores of iRNA-m5C, iRNAm5C-PseDNC and PEA-m5C, so the AUROCs for these methods were not available