Table 6 Comparison with existing methods on the independent test sets
From: m5CPred-SVM: a novel method for predicting m5C sites of RNA
Species | Model | Sn (%) | Sp (%) | Pre (%) | Acc (%) | Mcc | F1-score | AUROCa |
|---|---|---|---|---|---|---|---|---|
H. sapiens | RNAm5Cfinder | 37.7 | 88.4 | 76.5 | 63.1 | 0.303 | 0.505 | 0.635 |
iRNA-m5C | 42.1 | 46.4 | 43.9 | 44.2 | -0.116 | 0.429 | – | |
iRNAm5C-PseDNC | 4.35 | 97.1 | 60.1 | 50.7 | 0.039 | 0.081 | – | |
RNAm5CPred | 71.0 | 66.7 | 68.1 | 68.9 | 0.377 | 0.695 | 0.772 | |
our method | 75.4 | 79.7 | 78.8 | 77.5 | 0.551 | 0.77 | 0.858 | |
M. musculus | RNAm5Cfinder | 38.6 | 78.9 | 64.5 | 58.8 | 0.191 | 0.483 | 0.593 |
iRNA-m5C | 0.61 | 99.8 | 75.1 | 50.2 | 0.032 | 0.012 | – | |
our method | 67.9 | 74.9 | 73.0 | 71.4 | 0.429 | 0.704 | 0.775 | |
A. thaliana | iRNA-m5C | 72.4 | 75.6 | 73.5 | 74.1 | 0.481 | 0.729 | – |
PEA-m5C | 43.2 | 45.4 | 43.8 | 44.3 | -0.114 | 0.454 | – | |
our method | 75.5 | 76.1 | 76.0 | 75.8 | 0.516 | 0.757 | 0.836 |