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Fig. 6 | BMC Bioinformatics

Fig. 6

From: Inferring chromosome radial organization from Hi-C data

Fig. 6

Radial arrangement of CTs in irregularly shaped neutrophil nuclei. a Pairwise inter-chromosomal strong interaction pattern matrix for neutrophil Hi-C data. b 2D PCA projection of the pairwise inter-chromosomal strong interaction pattern matrix obtained from neutrophil Hi-C data. In neutrophil cells, chr2 (blue color) and chr18 (green color) occupy radial positions near nuclear envelope. c The radial distance profiles of 2 CTs (chr2, and chr18) in neutrophils obtained from the selected model cluster (# of models in the selected clusters: 100). d Comparison of predicted tuned CT distances from neutrophil Hi-C data and lymphoblastoid microscopy imaging data shows important differences between these cell types

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