From: Predicting substitutions to modulate disorder and stability in coiled-coils
CBspath | CBsclique | direct pathways | ||||
---|---|---|---|---|---|---|
N-term | 2nd half | C-term CB | N-term | C-term | ||
Wild type | 195, 25 | 19, 8, 6 | 11 | 32 | 35 | 11 |
V315D | 209 | 28, 9 | – | 23 | 65 | 17 |
L322D | 166, 24 | 25 | – | 32 | 58 | 31 |
L336D | 95, 89 | 16 | – | 36 | ||
V346D | 123, 20, 19, 19, 19 | 15, 9 | 19 | 30 | 63 | 4 |
I353D | 169, 16, 4, 18 | 17 | 20 | 36 | 55 | 12 |
E364F | 211 | 24 | – | 33 |