Table 1 Filtration criteria to sieve homologous sequences in each PSI-search iteration
From: Inter-protein residue covariation information unravels physically interacting protein dimers
Homolog filtration criteria | Â |
|---|---|
Sequence length | At least 80% of the query length but 78% in special cases |
Sequence identity | Sequence identity of at least 40% [70] but 25%, 30% or 35% in special cases |
Bit score | Bit score threshold of 0.5 \(\times\) monomer sequence length [42] and 0.45 \(\times\) monomer sequence length in special cases |
E-value | E-value smaller than 0.0001 |
Overlap length | Overlap length threshold of at least 90% but 70%, 80% or 85% in special cases |