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Table 1 Studies and strategies used to identify response genes/proteins

From: H2V: a database of human genes and proteins that respond to SARS-CoV-2, SARS-CoV, and MERS-CoV infection

Study1

Type

Strategy

SARS-CoV-2

SRA: SRP257667

DEG

b

https://doi.org/10.1101/2020.06.17.156455

DEG

a

PMID: 32358202

DEG

c

PMID: 32353859

PPI

a

https://doi.org/10.1101/2020.06.17.156455

PPI

a

PMID: 33060197

PPI

a

PMID: 32408336

DEP

a

https://doi.org/10.1101/2020.06.17.156455

DEP

a

PMID: 32645325

DPP

a

https://doi.org/10.1101/2020.06.17.156455

DPP

a

PMID: 32877642

DPP

a

PMID: 32408336

DTP

a

https://doi.org/10.1101/2020.06.17.156455

DUP

a

PMID: 32492406

SAP

a

https://doi.org/10.1101/2020.05.02.20088666

SAP

a

SARS-CoV

PMID: 32358202

DEG

c

PMID: 23935999

DEG

d

PMID: 20090954

DEG

d

PMID: 33060197

PPI

a

https://doi.org/10.1101/2020.06.17.156455

PPI

a

PMID: 15784933

DEP

a

MERS-CoV

PMID: 32223537

DEG

a

GEO: GSE81909

DEG

d

GEO: GSE79458

DEG

d

PMID: 33060197

PPI

a

  1. 1If a PMID was not available, an alternative database accession number is used
  2. a: Response genes/proteins were extracted from the journal article
  3. b: Response genes/proteins were identified from RNA-seq data using RaNA-seq, with p < 0.05 and |log2(fold change)|> 1 at any timepoint post infection
  4. c: Response genes/proteins were identified from read counts from GEO using DESeq2, with p < 0.05 and |log2(fold change)|> 1 at any timepoint post infection
  5. d: Response genes/proteins were identified from the expression matrix from GEO using limma, with p < 0.05 and |log2(fold change)|> 1 at any timepoint post infection