Fig. 7
From: DRPnet: automated particle picking in cryo-electron micrographs using deep regression
Single particle analysis 3D reconstruction outcomes. Left and middle columns compare the superimposed 3D reconstructions rendered as isosurfaces colored to represent local resolution variations generated from DRPnet-picked (a, d, g) or RELION template-based picked particles (b, e, h), respectively. The 3D reconstruction isosurfaces are colored such that higher resolution regions are colored in blue, and red represents less well-resolved regions (see color scale on left). The right column (c, f, i) contains corresponding masked Fourier Shell Correlation curves for 3D reconstructions, performed with or without symmetry, using DRPnet-picked or RELION TBA, with horizontal line indicating the gold standard (0.143) FSC cutoff. The top row shows 3D reconstructions from EMPIAR-10005 (TRPV1) , the middle row from EMPIAR-10061 (\(\beta\)-galactosidase) and last row from EMPIAR-10017 (\(\beta\)-galactosidase)