Table 3 Methods Comparison in Regression Tasks
From: Dynamic incorporation of prior knowledge from multiple domains in biomarker discovery
Method | Lasso | RRF | Know-GRRF | |||||
|---|---|---|---|---|---|---|---|---|
Prior 1 | Prior 2 | Prior 3 | ||||||
Freq>50% | Stepwise | Freq>50% | Stepwise | Freq>50% | Stepwise | |||
Scenario 1 | ||||||||
JI | 0.91a | 0.07 | 0.28 | 0.54 | 0.33 | 0.54 | 0.56 | 0.48 |
TPR | 1.00 | 0.20 | 0.70 | 0.70 | 0.70 | 0.70 | 1.00 | 1.00 |
FPR | 0.01 | 0.22 | 0.17 | 0.03 | 0.12 | 0.03 | 0.09 | 0.12 |
FN | – | 2, 3, 4, 5, 6, 9, 10 | 6, 7, 10 | 6, 7, 10 | 2, 3, 4 | 2, 3, 4 | – | – |
Scenario 2 | ||||||||
JI | 0.09 | 0.11 | 0.25 | 0.28 | 0.26 | 0.47 | 0.63a | 0.53 |
TPR | 0.10 | 0.30 | 0.70 | 0.50 | 0.60 | 0.80 | 1.00 | 1.00 |
FPR | 0.01 | 0.19 | 0.20 | 0.09 | 0.14 | 0.08 | 0.07 | 0.10 |
FN | 2, 3, 4, 5, 6, 7, 8, 9, 10 | 1, 2, 3, 4, 7, 8, 9 | 6, 8, 9 | 4, 6, 7, 8, 9 | 1, 2, 3, 4 | 3, 4 | – | – |
Scenario 3 | ||||||||
JI | 0.67 | 0.19 | 0.29 | 0.57 | 0.26 | 0.47 | 0.56 | 0.67a |
TPR | 1.00 | 0.50 | 0.70 | 0.80 | 0.60 | 0.80 | 1.00 | 1.00 |
FPR | 0.06 | 0.18 | 0.16 | 0.04 | 0.14 | 0.08 | 0.09 | 0.06 |
FN | – | 1, 3, 5, 7, 8 | 7, 8, 10 | 7, 8 | 1, 2, 3, 5 | 1, 3 | – | – |