Accurately estimating the length distributions of genomic micro-satellites by tumor purity deconvolution

BMC Bioinformatics

Table 5 Key indicators of ELMSI corresponding to different read lengths

Number of MSIs	Read length	Coverage	Accuracy	Recall	Precision	Gain	MCC
20	100	30 ×	0.31	0.45	0.5	0	-0.25
		60 ×	0.33	0.5	0.5	0	-0.5
		100 ×	0.31	0.45	0.5	0	-0.52
		120 ×	0.36	0.55	0.52	0.05	-0.46
	150	30 ×	0.31	0.45	0.5	0	-0.25
		60 ×	0.37	0.5	0.59	0.15	-0.45
		100 ×	0.46	0.6	0.6	0.3	-0.36
		120 ×	0.42	0.55	0.65	0.25	-0.40
	200	30 ×	0.5	0.65	0.68	0.35	-0.33
		60 ×	0.49	0.57	0.65	0.1	-0.55
		100 ×	0.48	0.7	0.61	0.25	-0.34
		120 ×	0.52	0.7	0.67	0.35	-0.32
	250	30 ×	0.6	0.75	0.75	0.5	-0.25
		60 ×	0.54	0.7	0.7	0.4	-0.3
		100 ×	0.55	0.75	0.69	0.2	-0.38
		120 ×	0.58	0.75	0.71	0.25	-0.34
50	100	30 ×	0.43	0.6	0.6	0.2	-0.4
		60 ×	0.37	0.55	0.54	0.08	-0.46
		100 ×	0.45	0.63	0.61	0.23	-0.38
		120 ×	0.36	0.55	0.52	0.05	-0.46
	150	30 ×	0.51	0.68	0.63	0.35	-0.33
		60 ×	0.45	0.63	0.61	0.23	-0.38
		100 ×	0.48	0.58	0.62	0.05	-0.45
		120 ×	0.47	0.73	0.63	0.45	-0.28
	200	30 ×	0.51	0.7	0.65	0.45	-0.32
		60 ×	0.61	0.78	0.64	0.5	-0.24
		100 ×	0.52	0.63	0.67	0.15	-0.40
		120 ×	0.56	0.75	0.68	0.4	-0.28
	250	30 ×	0.53	0.7	0.68	0.38	-0.31
		60 ×	0.57	0.78	0.7	0.23	-0.36
		100 ×	0.61	0.7	0.67	0.35	-0.32
		120 ×	0.59	0.75	0.7	0.25	-0.33

ISSN: 1471-2105