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Table 1 Median accuracy results obtained from the application of Models I, II, and III to the 1000 bootstrap samples generated (T, tumor neoplastic astrocytes; N, normal astrocytes; EN, elastic net; NB, Naïve Bayes: MSE, mean squared error; AUC, area under the precision-recall curve; Miscl, misclassifications; Vars, nr. of variables selected)

From: Tracking intratumoral heterogeneity in glioblastoma via regularized classification of single-cell RNA-Seq data

Classes

Model

Vars

Miscl

MSE

AUC

   

Train

Test

Train

Test

Train

Test

I - T-core vs. T-periphery

EN

83

10

7

0.029

0.047

0.97

0.94

II - T-periphery vs. N-periphery

EN

85

3

4

0.020

0.037

0.99

0.96

III - T-core/periphery vs. N-periphery

EN

76

1

2

0.005

0.012

0.997

0.982

 

Twiner

76

0

2

0.003

0.011

1

0.982

 

NBEN

76

5

6

0.009

0.034

0.996

0.979

 

NBtwiner

76

4

5

0.008

0.028

0.996

0.981