Fig. 2
From: Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt
Subcellular model schematics. a) Schematic representation of the VL model, which describes the dynamics of active destruction complexes (D), axin molecules (X), adhesion molecules (A), transcription molecules (T), Wnt target proteins (Y) and six pools of β-catenin (Ci, i=A,c,cT,o,oT and u). Reproduced with permission from [32]. b) Schematic representation of the Tan model which describes the dynamics of free and bound β-catenin in the cytosol-membrane (BC, NC) and nucleus (BN, NN), and free ligands in the cytosol-membrane (LC) and nucleus (LN). Reproduced with permission from [46]