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Table 3 AUC of the evaluated CNV callers on the MMRF CoMMpass WGS dataset

From: CNV Radar: an improved method for somatic copy number alteration characterization in oncology

CNV Caller AUC (gain) AUC (loss)
CNV Radar 0.94 0.90
CNVkit 0.93 0.65
CoNIFER – FCSVD0 0.45 0.59
CoNIFER – FCSVD1 0.23 0.45
CoNIFER – FCSVD2 0.11 0.37
CoNIFER – FCSVD3 0.08 0.28
CopywriteR 0.25 0.01
ExomeDepth 0.05 0.35
  1. AUC area under the receiver operating characteristic curve; CNV copy number variation; MMRF Multiple Myeloma Research Foundation; WGS whole genome sequencing; Radar rapid aberration detection and reporting; CoNIFER copy number inference from exome reads